Knee osteoarthritis is a degenerative joint disease that primarily affects the knee joint. It is characterized by the breakdown of cartilage in the knee, leading to pain, stiffness, and reduced mobility. This condition is most commonly seen in older adults, but can also occur in younger individuals as a result of injury or overuse. Research in the area of knee osteoarthritis focuses on understanding the underlying mechanisms of the disease, developing effective treatments to manage symptoms and slow disease progression, and improving the overall quality of life for individuals with this condition. This research may involve studies on the role of genetics, biomechanics, inflammation, and other factors in the development and progression of knee osteoarthritis. Additionally, researchers are exploring various treatment options such as medications, physical therapy, lifestyle modifications, and surgical interventions to help alleviate pain and improve joint function in individuals with knee osteoarthritis.